| 1. | Inhibition of after catarat formation by all - trans retinoic acid 全反式维甲酸对后发型白内障形成的抑制作用 |
| 2. | Progress of all - trans retinoic acid plus arsenic trioxide in treating active promyelocytic leukemia 5基因转录及活性的调控 |
| 3. | The fibrinolytic activity in leukemic cell lines and its alteration on all - trans retinoic acid treatment 2细胞耐药转运分子作用的研究 |
| 4. | Transcriptional and modulating activities of cyp3a5 gene induced by daunorubicin , dexamethasone and all - trans retinoic acid in some leukemia cell lines 白血病细胞系纤溶活性及全反式维甲酸对其影响 |
| 5. | The inhibitory effects of all - trans retinoic acid plus swine bile acid sodium salt on the proliferation and induction of differentiation in human ovarian cancer cell lines 全反式维甲酸联合猪胆酸钠对人卵巢癌细胞生长抑制作用的影响 |
| 6. | All - trans retinoic acid ( ra ) is one of the tumor chemotherapy agents , which can induce sh - sy5y cell to differentiate into neuron - like state and inhibit the sh - sy5y cellular growth . this process is a classic model in the research of neuron differentiation 全反式维甲酸作为临床上一种具有良好抗肿瘤作用的药物,它可诱导sh - sy5y细胞向神经元分化,并抑制其生长,这一模型一直是研究神经元分化的经典模型。 |
| 7. | The ebs of different days gained by means of hanging , suspending and suspending following hanging were processed by all - trans retinoic acid ( ra ) for 4 days . during this period , we observed the differentiation process and compared the differentiation ratio of es cells processed by means of hanging , suspending for several days . based on this study , we induced the ebs by ra of different concentration in order to study the effect of ra on the differentiation of es cells into neuron - like cells 首先从胚体( ebs )本身探讨es细胞内部调控诱导分化的机制,用悬浮培养、悬滴培养、悬浮转悬滴培养的方法培养出不同时间的ebs ,再加以ra处理,观察比较ebs对es细胞神经分化的影响;在此基础上,用不同浓度的ra处理ebs ,分析诱导剂ra对es细胞神经分化的影响。 |
| 8. | Restin was a novel gene isolated by our lab from differentiation tumor cell induced by all - trans retinoic acid in 1999 , and its molecular functions were not well understood . it mainly expresses in terminally differentiated cells . by transfection of restin into tumor cell , the cells were arrested in g1 phase and the cell proliferation was inhibited Restin是1999年本室在研究全反式维甲酸诱导细胞分化时克隆得到的一个人类未知功能的新基因,该基因主要表达于终末分化细胞,稳定转染该基因的细胞出现g1期阻滞,抑制细胞的增殖,提示restin与细胞周期的调控有关。 |